I had to leave earlier ParisJS, so I haven't seen your presentation, but people have given me some nice feedbacks! I like the way you take care of performance, it's cool!
But... I'm not sure that caching your result is a good idea. Almost by definition, Javascript is changing the DOM, so are the results eventually. A good practice is to cache-it, but manually is good enough, and at least you keep the power on the lists. I mention this because this is the feature you've highlighted with your benchmark.
Here an explanation of my words :
scope.ready(function(my, $) {
$("h2").addClass("mytest");
$("div").appendHtml("<h2>Test</h2>");
$("h2").addClass("mytest2");
});
>>> My new h2 doesn't have any class.
I'm looking forward to see how this will evolve! Keep going!