The proteins that exist today have developed into their present forms over the course of billions of years of natural evolution, passing through a vast evolutionary sieve.
My son went to Northeastern ('19) and now designs programming languages and can program skillfully in ANY language. I'm glad he went to Northeastern before this announced change. I feel my money spent at Northeastern was well worth it, not because it made him employable (it did), but because it gave him critical thinking and research skills. It would be sad if too many future Northeastern grads were limited to programming in Python or whatever the mainstream language of the decade is. "Batteries included" Python is great for the workforce but it may weaken basic development skills of undergrads. I'm glad I grew up in an era (1970-80s) when what mattered was sitting down with a manual or book and picking up a language in a weekend and, working with your friends, mastering it in a few weeks or months. A favorite memory that still astonishes me: in 1983 Andy Sudduth, one of my roommates and soon Olympic rowing medalist, built his own computer (a Heathkit), and with a paper due the next day, I offered to lend him my Kaypro-II so he could use WordStar. He said, "Thanks, but I'm going to put my own operating system on it [which he developed in his OS course], then I'm going to use my own full-screen editor I wrote, and then I'm going to write my paper using that editor." "You're going to do all that by tomorrow?", I asked. "Yes." And HE DID IT.
No, that is not true. I got treated for cancer two years ago (surgery and radiation), it was contained (not metastatic), I have twice since passed a Class 2 Medical. I talked to my Aeromedical Examiner, I talked with my treating doctors, they talked to each other, it worked out -- so far.
I wonder if there's an accurate record (time series) of what got canceled when, why, in what order, along with an accurate starting state for the whole SWA system. Then, for Monday morning quarterbacking, modelers and scientists could step through the meltdown in slow motion, and see, at each step, what they think could have been done differently.
No, I'm not especially knowledgeable, not more than others here. As a pilot, I have 42 years of experience flying through weather and helping get the word out w/r/t hurricanes, e.g., relaying info via ham radio in the West Indies from relays in Florida before getting hit by the storms, back in the 1970s when that was the way, so I have long interest in and appreciation of weather. But I do also have appreciation for my colleagues and their meteorological expertise. They have something called MinuteCast which in my experience has been very accurate in telling me when precipitation will begin or end (except when it is misty). Regarding my "forecasting actual rain is not very hard" remark, you are right that a "long in advance" forecast is hard, but I was talking about the short term. Specifically, a commenter had wanted to know if it was going to rain before going out to exercise, and for that example, I meant a forecast of precipitation was easy.
From talking with meteorologists, it seems forecasting actual rain is not very hard if you have enough current data on the state of the atmosphere. What can be difficult is mistiness that is just on the borderline between falling droplets and moisture just hanging in the air. Differences can be extremely local in nature. [I'm not a meteorologist, I program computers, but I'm a pilot so I have a pilot's appreciation of and contact with weather.]
Thanks. I think the new app coming out next month has a better UX. As for comparison with the default Weather app, I think the underlying forecast is more accurate. [Note, I work not on the app, but in back-end data. I'm happy to forward feedback to the people who work on the app.]
I like that Kirill Dubovikov built a weather station and showed others how. The more people who do this, the better, not just for education and skills, but in terms of gathering weather information that can help forecasters. He wrote, "the Weather app on my iPhone is not very good at making accurate forecasts," and I thought, "he must have been using the wrong app." I hope in addition to building weather stations and inspiring others to do so, he'll also give the AccuWeather app a try. [I work at AccuWeather; I admire the work my colleagues do to make and deliver accurate forecasts.] Even if Kirill prefers his weather station, I hope he'll use good apps to cross-check his station. Kirill can help in other ways. I speak Russian, so I volunteered to help beta-test the upcoming new app in Russian. My whole iPhone is in Russian at the moment. But Kirill is a native speaker.
I had the opposite reaction. I thought Fridman was a very good interviewer. I've talked with Donald Knuth a half dozen times over the last thirty years. I really enjoyed this interview. Knuth seemed relaxed and to be having a good time thinking about the questions and answering them. If Knuth is happy, I'm happy.
I also think the list is OK, not quite the list I would have picked, but close. But I'm puzzled how you would know it's a legit list if you have read none of the books?
In rural America, we have been importing doctors from other parts of the world because we don't have enough American doctors who want to serve outside the big cities and high-paid specialties.