I agree Dr. Bredesen's protocol probably can't hurt as it advocates a healthy lifestyle and diet, but there is NO evidence that it can prevent or reverse Alzheimers[1], as he claims. Also, Dr. Bredesen charges $1800+ for the protocol[2] in addition to selling branded supplements.
>In fact, we now have compelling epidemiological evidence that vaping almost doubles risk of cardiac events [1].
Somewhat misleading since more than half of those studied were smoking and vaping. From the study:
Among the 9,352 current and former e-cigarette users, 333 (3.6 percent) had experienced a heart attack at some point, with the highest percentage (6.1 percent) among those who used e-cigarettes daily. In the analysis, a quarter of the 2,259 people who currently used e-cigarettes were former smokers of conventional cigarettes and about 66 percent of current e-cigarette users were also current cigarette smokers.
When apoptosis fails, it's might be because p53 binds to foxo4 and gets stuck in the nucleus which prevents the p53 from getting to the mitochondria. In the experiment p53 in the paper, p53 unbound from foxo4 in the nuclease and bound to foxo4-dri and successfully flowed down the mitochondria so apoptosis could occur.
It is really sad that instead of discussing the merit of his argument, we are debating the quality of OP's site.
It is ridiculous that I have to police my site for low quality inbound links or risk getting banned (even more so for mom and pop webmasters who are more susceptible to link penalties). Lastly, if you are penalized, try recovering unless you are big brand like Overstock or JCPenney with millions per year in Adwords spend.
I really enjoyed this article. I wish she had given specific tips on how to think more creatively. She mentioned what happens "when" you think creatively, but did not really go into the "how."
I'm just learning ROR from an online tutorial (http://railstutorial.org/), and I wish I had this last week. For newbies like myself, I think installing the framework is sometimes such a big hurdle, it pushes one to give up early. Which is unfortunate, because I read the real challenges happen a few weeks in.
I had a weird issue where I had to reinstall xcode from the OS X DVD. Took a bit of Googling to figure that one out.