You cannot say it has "no long-term side effects". also a new flu vaccine is developed every year because influenza viruses naturally mutate quickly, as do any viruses. Don't just write things that you wish were true.
I would imagine it depends on the dose. An large dose of lsd would render just about anyone completely incoherent and possibly, absolutely insane. However, there is a reason many are gathering behind the idea of microdosing lsd for productivity. Here's an article on microdosing: https://motherboard.vice.com/en_us/article/gv5p5y/a-brief-hi...
The comparison of lsd to overclocking a processor is a pretty good one. Someone I know describes the experience in a similar way: "In normal waking life, data comes into my brain in a singular stream. On lsd my brain feels like it has the ability to process more at once- more streams."
Interesting things happen with all this input. Sensations get mixed around and felt in odd ways. For instance synesthesia... You make hear colors, or see emotions.