The problem is that the generics are equivalent to insulin from the 70's, when complications of type-1 diabetes were considered almost unavoidable. You can be super diligent and figure out how to manage your diet to make it work with the cheaper stuff, but that takes years of practice and conditioning. If you have to switch from something like humalog and an insulin pump, to injections of Regular insulin a two times a day or so, you are gonna be screwed.