I would expect taxation of all of these -- synthetics included -- to buy the appropriate certification and regulation.
It's also worth noting that the toxicity for some of these, including LSD, is so ridiculously low that as far as the science goes we should be much more concerned about moonshine than blotters.
It's also worth noting that the toxicity for some of these, including LSD, is so ridiculously low that as far as the science goes we should be much more concerned about moonshine than blotters.