Would be nice to think about how it compares to something like Pandoc which -- as far as I can tell from the Tutorial -- has all the expressiveness Nota has without being tied down to a particular output stack.
Also Nota doesn't absolve you of having to learn React, JS, etc. which is fine. Lightweight markup often winds up being a DSL over some more powerful underlying stack. But the goal is to separate authoring from styling. I.e. at the authoring stage you don't need to specify how a sidenote or a definition list would be implemented. Nota seems to mix these up.