Although it's a nice thought, the benefit of excel is it's comparatively low barrier-to-entry, ubiquity and transparency (in terms of other people being able to understand how a calculation was derived).
It's not realistic to expect everyone in a company to learn python, and I'm not convinced that replacing shitty excel documents with shitty code would introduce less errors.
Also the concept of 'minimum viable product' in excel is typically adding a couple of columns and adding titles to them. To develop something for others to use in python will take much longer.