On a previous project for our company, another dev and I were able to research and decide whether to use Angular or Knockout for a specific project. We concluded that for us, Knockout was the better choice because it seemed lighter-weight in terms of actually achieving our end goal which was simply doing reactive data-binding on the client side rather than having to do so with jQuery manually. We've since used it to create some pretty awesome user experiences that would have been a pain manually. To us, it didn't seem Angular would have been a poor choice. Rather, it was just that our goal was such that we did not need everything that Angular offers.
var ki = setInterval(function() { kinetigenClick(); kinetigenRelease(); }, 10);
Then later on at a certain point in the game, I had to stop it:
clearInterval(ki);