joefreeman

12일 전discuss

I've been building a text editor. It uses a server-client model, with native/terminal/web clients using a shared (local) server instance. It integrates LSP/tree-sitter/ripgrep/Git/etc, and has a concept of 'workspaces' to easily switch between projects.

I spend less time in an editor now, but it's been satisfying being able to take features I've enjoyed from other editors and customise - and it's oriented a bit more towards exploring code than editing. Key-bindings are arranged such that bare letters are for motions, Shift- variants are then used to extend selections, Ctrl- bindings are for buffer mutations, and leader-prefixed bindings are application level (e.g., opening pickers).

https://github.com/joefreeman/aether

joefreeman

3개월 전discuss

The workflow orchestration tools I've used over the past have been consistently unsatisfying, so I've been building my own. With Coflux (https://coflux.com), workflows are defined declaratively in plain Python with decorated functions (tasks). Workers connect to the orchestration server and get assigned work - calls to other tasks get intercepted and then re-scheduled by the server onto (potentially different) workers. Tasks are executed in pre-warmed, isolated processes, with low latency.

Beyond standard features (retries, caching, timeouts - enabled with attributes on the decorator), Coflux supports more novel features - like suspense (where a task can choose to go to sleep and get restarted when a result it depends on becomes available), memoisation (where steps within a run are aggressively cached so that you can re-run steps in a workflow without re-running upstream steps), and the ability to re-run a step in a different workspaces (with updated code, or in a different environment).

It turns out this works great for implementing agentic systems - you can provide references to tasks as tools to an LLM call and have the AI drive - tasks can be easily sandboxed. And Claude is very capable of using the CLI to interact with the orchestration server to submit workflows, investigate failed runs, make updates to workflows and re-run steps.

I'm trying to make sure it's easy to try out - there's a self-contained CLI that can be used to start the server (a single Docker container), run worker processes, and then interact with the server. The dev mode automatically restarts the workers as you make local changes. There's also a hosted UI for observing runs in real-time, where you can see the execution graph, access logs/metrics/assets/etc - it works without creating an account - the browser interacts with your orchestration server directly.

joefreeman

3년 전discuss

Genpax | Full-stack/product engineer | London, UK | ONSITE (hybrid/flexible) | https://www.genpax.co/

We're building a game-changing bacterial analysis platform. Using bioinformatics, we can help hospitals take early and effective action against outbreaks of MRSA and other pathogens.

Our goal is to radically increase the utility, scalability, and speed with which whole genome sequencing (WGS) data delivers infection control solutions for human and animal healthcare worldwide. This will enable proactive control at early stages of outbreaks, and appropriate responses to more dangerous or more antibiotic resistant strains. We have developed a unique solution to address the challenges and our goal is to provide access to these solutions in a fully scalable system.

I'm looking for an experienced full-stack (/'product') engineer to join our small engineering team - initially to focus on building out a novel interactive tree-based UI. There are some interesting challenges throughout the stack. We're using Python, GraphQL, React/TypeScript, Postgres and AWS, but open minded to adopting technologies that make sense.

Ideal candidates would:

  - Have an interest in working in BioTech/HealthTech (experience not necessary)
  - Have a strong academic background
  - Be based in/around London
  - Be self-motivated, and have experience working in a high-output team
  - Mention these things when getting in touch (and not be CC-ing every e-mail address on this page!)

£55-100k + equity, based on experience.

[email protected]

joefreeman

3년 전discuss

I think Maslow's Hierarchy of Needs is good place to get inspiration for this. It's guided my last two job roles in agritech and biotech. But I'm becoming aware that there seems to be an (inverse) correlation between how much money/funding is available as you go down the triangle.

joefreeman

3년 전discuss

Genpax | Full-stack/product engineer | London, UK | ONSITE (hybrid/flexible) | https://www.genpax.co/

We're building a game-changing bacterial analysis platform. Using bioinformatics, we can help hospitals take early and effective action against outbreaks of MRSA and other pathogens.

Our goal is to radically increase the utility, scalability, and speed with which whole genome sequencing (WGS) data delivers infection control solutions for human and animal healthcare worldwide. This will enable proactive control at early stages of outbreaks, and appropriate responses to more dangerous or more antibiotic resistant strains. We have developed a unique solution to address the challenges and our goal is to provide access to these solutions in a fully scalable system.

I'm looking for an experienced full-stack (/'product') engineer to join our small engineering team - initially to focus on building out a novel interactive tree-based UI. There are some interesting challenges throughout the stack. We're using Python, GraphQL, React/TypeScript, Postgres and AWS, but open minded to adopting technologies that make sense.

Ideal candidates would:

  - Have an interest in working in BioTech/HealthTech (experience not necessary)
  - Have a strong academic background
  - Be based in/around London
  - Be self-motivated, and have experience working in a high-output team
  - Mention these things when getting in touch (and not be CC-ing every e-mail address on this page!)

£55-100k + equity, based on experience.

[email protected]

joefreeman

3년 전discuss

> It's unfortunately easy to get a response that includes { "name": "grande latte" }

    type Item = {
        name: string;
        ...
        size?: string;

I'm not really following how this would avoid `name: "grande latte"`?

But then the example response:

    "size": 16

> This is pretty great!

Is it? It's not even returning the type being asked for?

I'm guessing this is more of a typo in the example, because otherwise this seems cool.

joefreeman

3년 전discuss

https://strawberry.rocks ;)

joefreeman

3년 전discuss

Genpax | Full-stack/frontend/product engineer | London, UK | ONSITE (hybrid/flexible) | https://www.genpax.co/

We're building a game-changing bacterial analysis platform. Using bioinformatics, we can help hospitals take early and effective action against outbreaks of MRSA and other pathogens.

Our goal is to radically increase the utility, scalability, and speed with which whole genome sequencing (WGS) data delivers infection control solutions for human and animal healthcare worldwide. This will enable proactive control at early stages of outbreaks, and appropriate responses to more dangerous or more antibiotic resistant strains. We have developed a unique solution to address the challenges and our goal is to provide access to these solutions in a fully scalable system.

I'm looking for an experienced frontend (or full-stack/'product') engineer to join our small engineering team - initially to focus on building out a novel interactive tree-based UI. There are some interesting challenges here (and throughout the stack). We're using Python, GraphQL, React/TypeScript, Postgres and AWS, but open minded to adopting technologies that make sense.

£55-100k + equity, based on experience.

[email protected]

joefreeman

3년 전discuss

Genpax | Full-stack/frontend/product engineer | London, UK | ONSITE (hybrid/flexible) | https://www.genpax.co/

We're building a game-changing bacterial analysis platform. Using bioinformatics, we can help hospitals take early and effective action against outbreaks of MRSA and other pathogens.

Our goal is to radically increase the utility, scalability, and speed with which whole genome sequencing (WGS) data delivers infection control solutions for human and animal healthcare worldwide. This will enable proactive control at early stages of outbreaks, and appropriate responses to more dangerous or more antibiotic resistant strains. We have developed a unique solution to address the challenges and our goal is to provide access to these solutions in a fully scalable system.

I'm looking for an experienced frontend (or full-stack/'product') engineer to join our small engineering team - initially to focus on building out a novel interactive tree-based UI. There are some interesting challenges here (and throughout the stack). We're using Python, GraphQL, React/TypeScript, Postgres and AWS, but open minded to adopting technologies that make sense.

£55-100k + equity, based on experience.

[email protected]

joefreeman

3년 전discuss

Genpax | Full-stack/frontend/product engineer | London, UK | ONSITE (hybrid/flexible) | https://www.genpax.co/

We're building a game-changing bacterial analysis platform. Using bioinformatics, we can help hospitals take early and effective action against outbreaks of MRSA and other pathogens.

Our goal is to radically increase the utility, scalability, and speed with which whole genome sequencing (WGS) data delivers infection control solutions for human and animal healthcare worldwide. This will enable proactive control at early stages of outbreaks, and appropriate responses to more dangerous or more antibiotic resistant strains. We have developed a unique solution to address the challenges and our goal is to provide access to these solutions in a fully scalable system.

I'm looking for an experienced frontend (or full-stack/'product') engineer to join our small engineering team - initially to focus on building out a novel interactive tree-based UI. There are some interesting challenges here (and throughout the stack). We're using Python, GraphQL, React/TypeScript, Postgres and AWS, but open minded to adopting technologies that make sense.

£55-100k + equity, based on experience.

[email protected]

joefreeman

3년 전discuss

Genpax | Full-stack/frontend/product engineer | London, UK | ONSITE (hybrid/flexible) | https://www.genpax.co/

We're building a game-changing bacterial analysis platform. Using bioinformatics, we can help hospitals take early and effective action against outbreaks of MRSA and other pathogens.

Our goal is to radically increase the utility, scalability, and speed with which whole genome sequencing (WGS) data delivers infection control solutions for human and animal healthcare worldwide. This will enable proactive control at early stages of outbreaks, and appropriate responses to more dangerous or more antibiotic resistant strains. We have developed a unique solution to address the challenges and our goal is to provide access to these solutions in a fully scalable system.

I'm looking for an experienced frontend (or full-stack/'product') engineer to join our small engineering team - initially to focus on building out a novel interactive tree-based UI. There are some interesting challenges here (and throughout the stack). We're using Python, GraphQL, React/TypeScript, Postgres and AWS, but open minded to adopting technologies that make sense.

£55-100k + equity, based on experience.

[email protected]

joefreeman

4년 전discuss

Genpax | Engineers (full stack, frontend/backend, product, devops) | London, UK | ONSITE (hybrid/flexible) | https://www.genpax.co/

Genpax is building a game-changing bacterial analysis platform. Using bioinformatics, we can help hospitals take early and effective action against outbreaks of MRSA and other pathogens. This is an opportunity to have a real-world impact on thousands of lives each year.

At Genpax our goal is to radically increase the utility, scalability, and speed with which whole genome sequencing (WGS) data delivers infection control solutions for human and animal healthcare worldwide. This will enable proactive control at early stages of outbreaks, and to respond appropriately to more dangerous or more antibiotic resistant strains. We have developed unique solutions to address the challenges and our goal is to provide access to these solutions in a fully scalable system.

There are really interesting engineering problems to be solved: scaling and optimising our analysis pipeline and the bioinformatics algorithms we use; building out our interactive graph-based user-facing product; developing cryptographic techniques for analysis of anonymised data. At the moment we're using Python, GraphQL, React/TypeScript, Postgres and AWS.

£45-95k + equity, based on experience.

[email protected]

joefreeman

4년 전discuss

Genpax | Engineers (full stack, frontend/backend, product, devops) | London, UK | ONSITE (hybrid/flexible) | https://www.genpax.co/

Genpax is building a game-changing bacterial analysis platform. Using bioinformatics, we can help hospitals take early and effective action against outbreaks of MRSA and other pathogens. This is an opportunity to have a real-world impact on thousands of lives each year.

At Genpax our goal is to radically increase the utility, scalability, and speed with which whole genome sequencing (WGS) data delivers infection control solutions for human and animal healthcare worldwide. This will enable proactive control at early stages of outbreaks, and to respond appropriately to more dangerous or more antibiotic resistant strains. We have developed unique solutions to address the challenges and our goal is to provide access to these solutions in a fully scalable system.

There are really interesting engineering problems to be solved: scaling and optimising our analysis pipeline and the bioinformatics algorithms we use; building out our interactive graph-based user-facing product; developing cryptographic techniques for analysis of anonymised data. At the moment we're using Python, GraphQL, React/TypeScript, Postgres and AWS.

£45-95k + equity, based on experience.

[email protected]

joefreeman

4년 전discuss

Thanks for posting this, and your learngenomics.dev resource looks great - I'm looking forward to reading this though. I recently started working as an engineering manager/lead in a genomics startup (https://www.genpax.co), and I've been picking this up as I go. I've also started working my way through the 'Micro binfie' podcast, which is great.

Our company values software quality and we're very product focussed. We're actively hiring in London: https://news.ycombinator.com/item?id=33423547

joefreeman

4년 전discuss

Genpax | Engineers (full stack, frontend/backend, product, devops) | Notting Hill, London, UK | ONSITE (hybrid/flexible) | https://www.genpax.co/

Genpax is building a game-changing bacterial analysis platform. Using bioinformatics, we can help hospitals take early and effective action against outbreaks of MRSA and other pathogens. This is an opportunity to have a real-world impact on thousands of lives each year.

At Genpax our goal is to radically increase the utility, scalability, and speed with which whole genome sequencing (WGS) data delivers infection control solutions for human and animal healthcare worldwide. This will enable proactive control at early stages of outbreaks, and to respond appropriately to more dangerous or more antibiotic resistant strains. We have developed unique solutions to address the challenges and our goal is to provide access to these solutions in a fully scalable system.

There are really interesting engineering problems to be solved: scaling and optimising our analysis pipeline and the bioinformatics algorithms we use; building out our interactive graph-based user-facing product; developing cryptographic techniques for analysis of anonymised data. At the moment we're using Python, GraphQL, React/TypeScript, Postgres and AWS.

£45-95k + equity, based on experience.

[email protected]

joefreeman

4년 전discuss

Genpax | Engineers (full stack, frontend/backend, product, devops) | Notting Hill, London, UK | ONSITE (hybrid/flexible) | https://www.genpax.co/

Genpax is building a game-changing bacterial analysis platform. Using bioinformatics, we can help hospitals take early and effective action against outbreaks of MRSA and other pathogens. This is an opportunity to have a real-world impact on thousands of lives each year.

At Genpax our goal is to radically increase the utility, scalability, and speed with which whole genome sequencing (WGS) data delivers infection control solutions for human and animal healthcare worldwide. This will enable proactive control at early stages of outbreaks, and to respond appropriately to more dangerous or more antibiotic resistant strains. We have developed unique solutions to address the challenges and our goal is to provide access to these solutions in a fully scalable system.

We already have a world-class scientific team of bioinformaticians, and we're building out an engineering team to match. There are really interesting engineering problems to be solved: scaling and optimising our analysis pipeline and the bioinformatics algorithms we use; building out our interactive graph-based user-facing product; developing cryptographic techniques for analysis of anonymised data. We're still in early stages - so far we’re using Python, GraphQL, React/TypeScript, Postgres and AWS.

£45-95k + equity, based on experience.

[email protected]

joefreeman

4년 전discuss

Genpax | Engineers (full stack, frontend/backend, product, devops) | Notting Hill, London, UK | ONSITE (hybrid/flexible) | https://www.genpax.co/

Genpax is building a game-changing bacterial analysis platform. Using bioinformatics, we can help hospitals take early and effective action against outbreaks of MRSA and other pathogens. This is an opportunity to have a real-world impact on thousands of lives each year.

At Genpax our goal is to radically increase the utility, scalability, and speed with which whole genome sequencing (WGS) data delivers infection control solutions for human and animal healthcare worldwide. This will enable proactive control at early stages of outbreaks, and to respond appropriately to more dangerous or more antibiotic resistant strains. We have developed unique solutions to address the challenges and our goal is to provide access to these solutions in a fully scalable system.

We already have a world-class scientific team of bioinformaticians, and we're building out an engineering team to match. There are really interesting engineering problems to be solved: scaling and optimising our analysis pipeline and the bioinformatics algorithms we use; building out our interactive graph-based user-facing product; developing cryptographic techniques for analysis of anonymised data. We're still in early stages - so far we’re using Python, GraphQL, React/TypeScript, Postgres and AWS.

£45-95k + equity, based on experience.

[email protected]

joefreeman

4년 전discuss

Genpax | Engineers (full stack, frontend/backend, product, devops) | Notting Hill, London, UK | ONSITE (hybrid/flexible) | https://www.genpax.co/

Genpax is building a game-changing bacterial analysis platform. Using bioinformatics, we can, for example, help hospitals take early and effective action against outbreaks of MRSA. This is an opportunity to have a real-world impact on thousands of lives each year.

At Genpax our goal is to radically increase the utility, scalability, and speed with which whole genome sequencing (WGS) data delivers infection control solutions for human and animal healthcare worldwide. This will enable proactive control at early stages of outbreaks, and to respond appropriately to more dangerous or more antibiotic resistant strains. We have developed unique solutions to address the challenges and our goal is to provide access to these solutions in a fully scalable system.

We already have a world-class scientific team of bioinformaticians, and we're building out an engineering team to match. There are really interesting engineering problems to be solved: scaling and optimising our analysis pipeline and bioinformatics algorithms; building out our interactive graph-based user-facing product; developing cryptographic techniques for analysis of anonymised data. We’re still in early stages - so far we’re using Python, GraphQL, React/TypeScript and AWS.

£45-95k + equity, based on experience.

[email protected]

joefreeman

6년 전discuss

I'm about to start at Optimal (in London). It's not exactly conservation, but I like to think it's not far from it. Some details on the Who's Hiring post [1]. Best of luck otherwise.

[1] https://news.ycombinator.com/item?id=23702401

joefreeman

6년 전discuss

I alternate between a (now ageing 9350-model) XPS 13 running Ubuntu and a (newish) MacBook Pro (for work), so perhaps my experience is interesting to some.

I like both, but switching between the two is a bit jarring. The different keyboard layout is particularly annoying. Maybe this is worse with a British keyboard though. I switched the Mac to use the 'PC' layout, which helps a bit, but adapting between the cmd-ctrl-fn is difficult. And there are inconsistencies in the readline behaviour that I haven't worked out. I'm fairly indifferent to the feel of the keyboard - maybe a slight preference for the XPS.

I like the 16:9 ratio of the XPS, but not a big deal.

The 20.04 update has been such an improvement. The fan used to be constantly running, maybe because of the previously-experimental fractional scaling, but since the update this runs so smooth. If anyone from Gnome/Ubuntu reads this: thank you!

The trackpad on the MacBook is obviously nice: support for gestures and the bigger area. I can't stand the touch bar - I'm constantly accidentally pressing buttons. TouchID is nice - the fingerprint reader in this new version sounds good.

Few other things that are better on the MBP: speakers, brightness (especially the auto-adjusting brightness), and webcam (this version of the XPS has the webcam below the screen, which sucks).

I don't make any use of the touchscreen on the XPS and I haven't got around to turning it off from the BIOS. Seems kind of wasteful.

The coil whine on the XPS is really bad. Interested to know if this is fixed/better on the newer models?

I replaced the battery on the XPS recently, but turns out the battery isn't as official as Amazon promised so the LED occasionally does an angry flashing sequence. But yay for being able to replace this.

Also the Dell support turned out to be pretty good. At one point there was an issue with my screen and they sent a guy to my house to replace the screen for free.

joefreeman

Submissions

Show HN: Topical – Elixir library for synchronising state to web clients

Hundreds arrested as crime chat network cracked

ElixirConf 2016 – Keynote by José Valim

Grandfather Paradox

Sam Aaron - Hacking Overtone - Live Arnolfini

Queen's speech: App lets you text like Her Majesty

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