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3년 전discuss

Frameshift Genomics | Backend Developer, Full Stack, Database | Remote / Boston, MA Frameshift Genomics (http://frameshift.io) is hiring backend and full-stack web developers to work on our genomic diagnostic, analytics, and visualization platform. Genomic data is growing at such a rate that it is becoming one of the biggest types of data in the world. This data holds enormous insights and value in fields such as drug development, personalized medicine, disease diagnosis, disease research, crop development, and more. Our goal is to provide a self-serve product to empower doctors, researchers, and biologists to directly bring their expertise to bear.

The successful applicants will be developing new features for our flagship product, Mosaic, and/or developing (and potentially leading the development of) our real-time variant warehouse, which will store and query millions of variants. Our technology stack is postgres, node, and vue.js. Specialized knowledge of biology or genomics is not required.

Remuneration will include both a competitive salary and stock in Frameshift Genomics. Contact us at [email protected]

4년 전discuss

Frameshift Genomics | Backend Developer, Full Stack, Database | Remote / Boston, MA

Frameshift Genomics (http://frameshift.io) is hiring backend and full-stack web developers to work on our genomic diagnostic, analytics, and visualization platform. Genomic data is growing at such a rate that it is becoming one of the biggest types of data in the world. This data holds enormous insights and value in fields such as drug development, personalized medicine, disease diagnosis, disease research, crop development, and more. Our goal is to provide a self-serve product to empower doctors, researchers, and biologists to directly bring their expertise to bear.

The successful applicants will be developing new features for our flagship product, Mosaic, and/or developing (and potentially leading the development of) our real-time variant warehouse, which will store and query millions of variants. Our technology stack is postgres, node, and vue.js. Specialized knowledge of biology or genomics is not required.

Remuneration will include both a competitive salary and stock in Frameshift Genomics. Contact us at [email protected]

6년 전discuss

Frameshift Genomics | Backend Developer, Full Stack, Database | Boston, MA

Frameshift Genomics (http://frameshift.io) is hiring backend and full-stack engineers to work on creating a genomic analytics and visualization platform. Genomic data is growing at a rate where it will become one of (if not the) biggest types of data in the world. This data holds enormous insights and value in fields such as drug development, personalized medicine, disease diagnosis, crop development, and more. However, only a fraction of that potential is currently being realized.

The successful applicant will be developing (potentially leading the development of) our real-time variant warehouse, which powers our analytics and visualization platform. The warehouse is built on postgres.

Remuneration will include both a competitive salary and stock in Frameshift Genomics. Contact us at [email protected]

8년 전discuss

Frameshift Genomics | Full Stack Web Developers | Boston, MA

Frameshift Genomics (http://frameshift.io) is hiring full-stack web developers to work on the iobio project (http://iobio.io), building a real-time genomics visualization and analysis platform.

We need help creating web applications with functionality ranging from visualizing terabytes of biological data to fine grained interrogation of disease causing mutations. To support these apps, we are looking to create systems that will analyze and search huge amounts of genomic data, support our visualization and collaboration needs, and provide a robust API. Expertise in web development and/or database design/optimization is desired. Our technology stack is postgres, node, and vue.js. Specialized knowledge of biology or genomics is not required.

The successful applicant will be involved in both designing and building these systems and apps and will also help with our goal of simplifying genomic analysis in order to move toward precision medicine.

Remuneration will include both a competitive salary and stock in Frameshift Genomics. Contact us at [email protected]

8년 전discuss

Frameshift Genomics | Full Stack Web Developers | Boston, MA

Frameshift Genomics (http://frameshift.io) is hiring full-stack web developers to work on the iobio project (http://iobio.io), building a real-time genomics visualization and analysis platform.

We need help creating web applications with functionality ranging from visualizing terabytes of biological data to fine grained interrogation of disease causing mutations. To support these apps, we are looking to create systems that will analyze and search huge amounts of genomic data, support our visualization and collaboration needs, and provide a robust API. Expertise in web development and/or database design/optimization is desired. Our technology stack is postgres, node, and vue.js. Specialized knowledge of biology or genomics is not required.

The successful applicants will be involved in both designing and building these systems and apps and will also help with our goal of simplifying genomic analysis in order to move toward precision medicine.

Remuneration will include both a competitive salary and stock in Frameshift Genomics. Contact us at [email protected]

8년 전discuss

Frameshift Genomics | Full Stack Web Developers | Boston, MA

Frameshift Genomics (http://frameshift.io) is hiring full-stack web developers to work on the iobio project (http://iobio.io), building a real-time genomics visualization and analysis platform.

We need help creating web applications with functionality ranging from visualizing terabytes of biological data to fine grained interrogation of disease causing mutations. To support these apps, we are looking to create systems that will analyze and search huge amounts of genomic data, support our visualization and collaboration needs, and provide a robust API. Expertise in web development and/or database design/optimization is desired. Our technology stack is postgres, node, and vue.js.

The successful applicant will be involved in both designing and building these systems and apps and will also help with our goal of simplifying genomic analysis in order to move toward precision medicine.

Remuneration will include both a competitive salary and stock in Frameshift Genomics. Contact us at [email protected]

9년 전discuss

Frameshift Genomics | Full Stack Web Developers | Boston, MA

Frameshift Genomics (http://frameshift.io) is hiring full-stack web developers to work on the iobio project (http://iobio.io), building a real-time genomics visualization and analysis platform.

We need help creating web applications with functionality ranging from visualizing terabytes of biological data to fine grained interrogation of disease causing mutations. To support these apps, we are looking to create systems that will analyze and search huge amounts of genomic data, support our visualization and collaboration needs, and provide a robust API. Expertise in web development and/or database design/optimization is desired. Our technology stack is postgres, node, and vue.js.

The successful applicant will be involved in both designing and building these systems and apps and will also help with our goal of simplifying genomic analysis in order to move toward precision medicine.

Remuneration will include both a competitive salary and stock in Frameshift Genomics. Contact us at [email protected]

9년 전discuss

Frameshift Genomics | Full Stack Web Developers | Boston, MA

Frameshift Genomics (http://frameshift.io) is hiring full-stack web developers to work on the iobio project (http://iobio.io), building a real-time genomics visualization and analysis platform.

We need help creating web applications with functionality ranging from visualizing terabytes of biological data to fine grained interrogation of disease causing mutations. To support these apps, we are looking to create systems that will analyze and search huge amounts of genomic data, support our visualization and collaboration needs, and provide a robust API. Expertise in web development and/or database design/optimization is desired. Our technology stack is postgres, node, and vue.js.

The successful applicant will be involved in both designing and building these systems and apps and will also help with our goal of simplifying genomic analysis in order to move toward precision medicine.

Remuneration will include both a competitive salary and stock in Frameshift Genomics. Contact us at [email protected]

9년 전discuss

Frameshift Genomics | Full Stack Web Developers | Boston, MA

Frameshift Genomics (http://frameshift.io) is hiring full-stack web developers to work on the iobio project (http://iobio.io), building a real-time genomics visualization and analysis platform.

We need help creating web applications with functionality ranging from visualizing terabytes of biological data to fine grained interrogation of disease causing mutations. To support these apps, we are looking to create systems that will analyze and search huge amounts of genomic data, support our visualization and collaboration needs, and provide a robust API. Our technology stack is postgres, node, and vue.js.

The successful applicant will be involved in both designing and building these systems and apps and will also help with our goal of simplifying genomic analysis in order to move toward precision medicine.

Remuneration will include both a competitive salary and stock in Frameshift Genomics. Contact us at [email protected]

Required Skills - JavaScript proficient - Experience building web applications - Can work effectively in a team environment

Desirable Skills - Database Experience, especially with scaling postgres - Experience building commercial grade web applications - Genomics/Biology experience - Web security experience - Javascript client framework experience (e.g. React, Vue) - Node.js - Security, data access control and authentication experience

Compensation - Competitive Salary - Stock

9년 전discuss

Frameshift Genomics and University of Utah | Full Stack Web Developers | Boston, MA SLC, Utah

Frameshift Genomics (http://frameshift.io) and the MarthLab (http://marthlab.org/) at the University of Utah are hiring full-stack web developers to work on the iobio project (http://iobio.io), building a real-time genomics visualization and analysis platform. We will only consider applicants physically located in Boston, MA seeking full-time employment, not contract work).

We need help creating web applications with functionality ranging from visualizing terabytes of biological data to fine grained interrogation of disease causing mutations. To support these apps, we are looking to create systems that will analyze and search huge amounts of genomic data, support our visualization and collaboration needs, and provide a robust API. We are built on a traditional server setup but require strong integration and access to cloud systems.

The successful applicant will be involved in both designing and building these systems and apps and will also help with our goal of simplifying genomic analysis, helping to usher in the world of precision medicine.

Remuneration will include both a competitive salary and stock in Frameshift Genomics. Contact us at [email protected]

9년 전discuss

Frameshift Genomics | Backend Engineers, Frontend Web Developers | Boston, MA

Frameshift Genomics (http://frameshift.io) is hiring backend engineers and web developers to work on the iobio project (http://iobio.io), building a real-time genomics analysis platform. Web developers will be creating web applications with functionality ranging from visualizing terabytes of biological data to fine grained interrogation of disease causing mutations that open the world of complex genomic analysis to medical professionals and scientists with limited or no experience in computational analysis. These applications are built on our technology stack, consisting of a node web service backend, which streams analysis results via websockets to the web applications, where results are visualized using D3. The successful applicant will be involved in further developing the iobio framework (client libraries and server), designing and building new web apps, and creating new visualizations. For backend engineers we are looking to create systems that will analyze huge amounts of genomic data, support the visualization and collaboration needs of our web apps, and provide a robust API for data visualization. We are built on AWS and are looking to leverage the cloud wherever possible, but will most likely require traditional server setups for clients with sensitive patient data. The successful applicant will be involved in both designing and building these systems. Remuneration will include both a competitive salary and stock in Frameshift Genomics. Contact us at [email protected]

9년 전discuss

Frameshift Genomics | Backend Engineers, Frontend Web Developers | Boston, MA

Frameshift Genomics (http://frameshift.io) is hiring backend engineers and web developers to work on the iobio project (http://iobio.io), building a real-time genomics analysis platform.

Web developers will be creating web applications with functionality ranging from visualizing terabytes of biological data to fine grained interrogation of disease causing mutations that open the world of complex genomic analysis to medical professionals and scientists with limited or no experience in computational analysis. These applications are built on our technology stack, consisting of a node web service backend, which streams analysis results via websockets to the web applications, where results are visualized using D3. The successful applicant will be involved in further developing the iobio framework (client libraries and server), designing and building new web apps, and creating new visualizations.

For backend engineers we are looking to create systems that will analyze huge amounts of genomic data, support the visualization and collaboration needs of our web apps, and provide a robust API for data visualization. We are built on AWS and are looking to leverage the cloud wherever possible, but will most likely require traditional server setups for clients with sensitive patient data. The successful applicant will be involved in both designing and building these systems. Remuneration will include both a competitive salary and stock in Frameshift Genomics. Contact us at [email protected]

9년 전discuss

Frameshift Genomics | Backend Engineers, Frontend Web Developers | Boston, MA

Frameshift Genomics (http://frameshift.io) is hiring backend engineers and web developers to work on the iobio project (http://iobio.io), building a real-time genomics analysis platform.

Web developers will be creating web applications with functionality ranging from visualizing terabytes of biological data to fine grained interrogation of disease causing mutations that open the world of complex genomic analysis to medical professionals and scientists with limited or no experience in computational analysis. These applications are built on our technology stack, consisting of a node web service backend, which streams analysis results via websockets to the web applications, where results are visualized using D3. The successful applicant will be involved in further developing the iobio framework (client libraries and server), designing and building new web apps, and creating new visualizations.

For backend engineers we are looking to create systems that will analyze huge amounts of genomic data, support the visualization and collaboration needs of our web apps, and provide a robust API for data visualization. We are built on AWS and are looking to leverage the cloud wherever possible, but will most likely require traditional server setups for clients with sensitive patient data. The successful applicant will be involved in both designing and building these systems. Remuneration will include both a competitive salary and stock in Frameshift Genomics. Contact us at [email protected]

10년 전discuss

Frameshift Genomics and the Marth Laboratory are hiring web developers to work on the iobio project (http://iobio.io), building a realtime genomics analysis platform. The project consists of developing web applications with functionality ranging from visualizing terabytes of biological data to fine grained interrogation of disease causing mutations that open the world of complex genomic analysis to medical professionals and scientists with limited or no experience in computational analysis. These applications are built on our technology stack, consisting of a node web service backend, which streams analysis results via websockets to the web applications, where results are visualized using D3.

The successful applicant will be involved in further developing the iobio framework (client libraries and server), building new web apps, creating new visualizations, and hardening current web apps. Remuneration will include both a competitive salary and stock in Frameshift Genomics. Contact us at [email protected]

Required Skills

  - JavaScript proficient
  - Experience building web applications
  - Can effectively work in a team environment using version  control (git/github)

Desirable Skills

  - Experience building commercial grade web applications
  - Genomics/Biology experience
  - Web security experience
  - Experience with testing frameworks
  - Node.js

Locations

  - Boston, MA
  - Salt Lake City, UT

Compensation

  - Competitive Salary
  - Stock in Frameshift Genomics

11년 전discuss

Absolutely, I meant to add above that the 23andme dataset has huge value due to its size. Also you bring up a good point about potential easy access to participants. If 23andme allows researchers to contact people who were of interest to their particular study and ask for more information, which could be as easy a questionnaire, that could be incredibly valuable. I don't agree with the above commenter that 23andme was a failure. Genomics is still incredibly young and we are just getting to the point where we can have an impact on the average persons life.

As for the 1000 genomes project, it was funded with government money (I think mostly the NIH, although the UK may have been involved too) therefore the data is free and open. The data was generated using illumina sequencers.

11년 전discuss

I figured I could add a little clarification to this comment.

* The human genome project created a "single" genome (thats not quite right, but close enough for this discussion). This was and is incredibly useful, but a single genome can only do so much. To answer population genomics questions (e.g. is this mutation common and therefore probably not disease causative) you need lots of people and the more the better.

* The 23andme dataset is not whole genome data, but instead some subset of genomic locations that they consider more interesting. Still valuable but not as much as whole genome data.

Also, for big whole genome datasets you can check out the 1000 Genomes Project, which has somewhere north of 2000 genomes. And there are many more big datasets in the works, which will continue to be incredibly useful!