There have been massive improvements in treatments in the last 5 years. Sure, cancer is far from being "cured" - but survival today is far better than 5 years ago for many forms.
Among many others:
- CAR T therapy going from lab to oncology suite (first launch 2017, but use rapidly growing)
- Liquid biopsy going from lab to PCP's office - starting with Grail Galleri and moving from there (yes, the NIH results were weak, but the idea of a liquid biopsy at all would be laughed off 10 years ago)
- Move of Atezolizumab and Tecentriq from infusion (hour) to injection (minutes) to increase availability
- Lower dose CT scanning for lung cancer, including for non-smokers
And a long line of immunotherapies that are making the leap from lab to chair right now.
The last 5 years have probably been the most exciting in cancer research since the launch of the monoclonal antibodies in the early 2010s. There is still incredibly far to go, but the trend is in the right direction: https://employercoverage.substack.com/p/decline-in-cancer-mo...
Radar is ineffective underwater because the radio waves are absorbed by the water. That is why there's no radar in use on submarines.
Sonar is not a valid solution here because it annoys the whales. Or at least high-power sonar, as used by the military, does. It would defeat the point.
No jets use or have ever used leaded products. Jets run on Jet-A, which is a close relative of kerosene. It has never been leaded. The purpose of lead was to prevent cylinders from prematurely detonating ("knocking") in internal combustion engines. Jets do not have any cylinders to knock; the fuel burns continually in an open combustion chamber.
You may have been thinking of 100LL (100 Low Lead) fuel for piston engined planes. Many airports stopped selling 100LL in January of 2022. The FAA has approved a lead-free replacement in fuels like UL94 that are steadily replacing 100LL.
There's lots of room to nitpick the evidence, but the studies are published:
> The relationship between age and job performance for Air Traffic Control Specialists (ATCSs) is an issue that has been revisited many times over the past few decades (Trites, 1961; Trites & Cobb, 1962; Cobb, 1968; VanDeventer & Baxter, 1984). Researchers have consistently found a negative relationship between controller age and performance across studies that have used different ATCS options (enroute, terminal), career stages (age at entry into training,current age on the job), and criterion measures (on-the-job ratings, academy performance) (Trites, 1961;Trites & Cobb, 1962; Cobb, 1968; VanDeventer & Baxter, 1984).
After the pharmacies got sued for filling opiate prescriptions (which were written by abusive doctors, but the pharmacies are the ones who got sued)[1], is it any surprise that Xanax and Adderall are being limited? If pharmacies are at risk for filling prescriptions that are more complex than antibiotics, the end result is that they make it harder to fill them.
The other way around. "Blank check companies" have existed for many many years, but were a relatively rare instrument and did very bespoke deals. Most investors never heard of them. In recent years, a standardized deal emerged that became known as a SPAC (and all the recent flavors of the month). If you look in SEC regulations, you'll see references to "blank check companies" all over the place.
My concern is not that AWS should be forced to host content they don't want. It's that AWS (and Apple, Facebook, and others) have misrepresented what they do.
It's no shock that DailyKos shouldn't have to host pro-Trump content. Nor should /theDonald have to host pro-Bernie content. We all agree that people can choose who to associate with, and that free association is important.
But AWS (and Facebook and others) didn't say "we're sites that present only one kind of content" the way /theDonald and DailyKos did. They presented themselves as universal tools for people to express themselves, build their own sites, install apps, etc.
So it comes as a shock when AWS says "we actually only want to support sites that present views that Jeff Bezos thinks are reasonable." And when Apple says "you can only download apps on your phone that we think do a good enough job moderating." And when Facebook bans people for posting wrong opinions.
The government can't and probably shouldn't force AWS to host content that Bezos doesn't agree with. It would be Amazon's right to host only content that is pro-Trump, or equally Amazon's right to only host content that is anti-Trump. But when Amazon presents something as a neutral utility but secretly enforces different rules, we can and should criticize them.
That's true even if all the content being removed today is garbage. I haven't seen any "worthwhile" content that's been affected by the recent moves, and I have never heard of any valuable speech on Parler. But I am still concerned that Apple gets to decide what apps I can install on my phone because they don't like the content. For every Apple (managed in California by socially liberal periople) there's a Walmart (managed in Arkansas by social conservatives) that will take the same powers and use them in a different way. Walmart is legally free to remove pro-BLM books from their online bookshelves, but we can and should criticize them if they do.
That's not how subsistence farming is counted in GDP and poverty statistics. The value of home production is still counted. If you are eating only $2 worth of rice per day, you are counted as poor whether you buy it or grow it.
In America, people would build their houses around an industrial zone and then complain about the industry -- this happens all the time. For some nuisances, like airports, it has broader impacts beyond just the industrial zone.
Yes. Spreading basins have become popular-ish in portions of California that have concentrated rainfall in the winter but high demand in the summer.[1]
In academic literature about criminal law, "incapacitation" has the very specific meaning that somebody who is in jail is not able to commit crimes on the street. It has nothing to do with their health (even if they may suffer a health impact).
Among many others:
- CAR T therapy going from lab to oncology suite (first launch 2017, but use rapidly growing)
- Approval of Keytruda and similar for many additional forms of cancer (see the 2021-2026 milestones here: https://www.drugs.com/history/keytruda.html )
- Liquid biopsy going from lab to PCP's office - starting with Grail Galleri and moving from there (yes, the NIH results were weak, but the idea of a liquid biopsy at all would be laughed off 10 years ago)
- Move of Atezolizumab and Tecentriq from infusion (hour) to injection (minutes) to increase availability
- Lower dose CT scanning for lung cancer, including for non-smokers
And a long line of immunotherapies that are making the leap from lab to chair right now.
The last 5 years have probably been the most exciting in cancer research since the launch of the monoclonal antibodies in the early 2010s. There is still incredibly far to go, but the trend is in the right direction: https://employercoverage.substack.com/p/decline-in-cancer-mo...