Finding an appropriate business model is situational and may evolve as you engage with the user community. You could start by working in public with an open source license [1]. Your initial focus is customer discovery and building a community of stakeholders willing to invest their time and accepting the adoption risk. Once you have advocates, they may have suggestions for an appropriate business model. For example, the existing non-profit may decide to apply for grants, keeping the work open source and acting as the fiscal sponsor for the project via open collective [2] supporting a paid position. In my experience, getting caught up on recapturing early investment, being concerned about secrecy / proprietary value, or being worried about a competitor are often not the best use of mental energy early on. Conversely, sharing more about your space and ideas may win you collaborators and potential customers you didn't anticipate. Alas, none of this advice may apply, the right approach is specific to a particular opportunity. Good luck & have fun.
Sid, Thank you for funding Arden Bio. Rheumatology patients and their clinicians are often left to throwing darts from afar, in series and often with significant & permanent function loss with each dart. Moreover, proper care of refractory rare diseases is not something that insurance funds: my otherwise excellent coverage expressly denies "investigatory" treatments, for example. As a small fiber neuropathic vasculitus patient with secondary Sjögren's I really look forward to progress in this field, it cannot happen soon enough. Best of luck in your own care and profile. - Clark
Heath Brothers' treatise, Switch: How to Change Things When Change Is Hard, describes three legs to facilitating a change: clear vision, sufficient motivation, and concrete first steps.
The title of this blog post hints at an important topic. However, I think even a single page summary or graphic from Switch may be more actionable. I don't love Switch's elephant analogy but it's good enough. It helped me with blind spots in my proposals.
Democracy is successful when it creates the business-regulatory environment and marketplace that let the private sector advance human welfare as well as technology.
Dissemination takes work. Materials in the right languages are needed. Finding the minimum necessary detail and visuals help. Delivery to new parents has to be done when they need the information, else they won't be receptive or remember. Then you need to get these materials into the birthing centers, to midwifes and nurses, etc. An evaluation component is also helpful to see if the approach can be improved, etc. Having this done in a repeatable way is important, every day there are new parents.
I don't see the price tag for this, but a few million dollars isn't all that much given the complexity of the dissemination challenge. It's probably a program but likely not an entire department. Curating knowledge and getting it to right people's attention at the right time is hard work. Did you see the materials they produce/disseminate?
After birth, when new parents are sleep deprived, is a uniquely stressful time when parents are bombarded with information. Advice on the Internet is prolific and often wrong, raising anxiety without providing needed context-sensitive guidance. It looks like this program was providing trustworthy materials and outreach to reduce infant death.
I think the worse-is-better philosophy is not well encapsulated with the 4 priorities given. Perhaps it is 4 completely different priorities. Here's a strawman.
1. Minimal -- the design and implementation must be the smallest as possible,
especially the scope (which should be deliberately "incomplete")
2. Timely -- the implementation must be delivered as soon as feasible, even if it comes before the design (get it working first, then figure out why)
3. Relevant -- the design and implementation must address important, unmet need, eschewing needs that are not urgent at the time (you can iterate or supplement)
4. Usable -- the implementation must be integrated with the existing, working and stable infrastructure (even if that integration causes design compromises)
The other dimensions, simplicity, correctness, consistency, and completeness are very nice to have, but they are not the primary drivers of this philosophy.
Thank you @jaboutboul. I appreciate that Linux works so well on Azure.
A substantial problem for the Linux ecosystem on Azure is that Azure Files is not POSIX compliant. With Container Apps, ephemeral storage is POSIX compliant. However, if you mount a persistent Azure Files file system and use it directly, some applications break. One workaround is to use rsync in the background to replicate data from ephemeral to Azure Files, but we can lose data this way (and ephemeral storage is limited to 8 GiB).
It'd also be nice if "Consumption Only" container apps would have more than 4GB of memory. It's so nice to use these.
My new bosh dishwasher does clean better and is quieter compared to prior bosh, that had to be replaced at the 7 year mark. This one is far more plastic and I expect it to last only 3-5 years.
Except that the one that lasts for 5 years will have 3 maintenance breakdowns during that time, where the appliance is unusable for 3-7 weeks while the service tech goes back and forth replacing components. I'd rather be stuck with the 20 old machine that has a few breakdowns but with simpler parts that could fit in the truck.
There is a business opportunity here, like Framework (with open specs), but for Induction cooktops, refrigerators, dishwashers, etc.
Tufts CTSI | Full-time | Remote, U.S. | Junior Research Software Engineer
Tufts CTSI (https://www.tuftsctsi.org/) is one of 60 NIH CTSA awardees. We are seeking a clinical data analyst / RSE to support our investigators with cohort discoveries, chart abstractions, data modeling, visualizations, and other data analysis needed for the preparation and performance of medical research grants. You would also help us grow our OHDSI (https://ohdsi.org) based research data warehouse (ETL from Epic EHR), work with RedCAP instruments, and automate operational processes. This role requires outstanding verbal and written literacy, a love of healthcare data, coupled with technical competence. We use Julia (esp. https://github.com/MechanicalRabbit/FunSQL.jl) for our database query work. This job is mostly researcher support and improving our ETLs; software we build/use is open source.
This job requires you reside in the U.S. without additional work permits. This is a junior position. This job advertisement is open but not yet posted. You could email me, [email protected] to apply. Thank you so much.
Tufts CTSI seeks a Project Manager to help us coordinate an international Oncology Network within the OHDSI (https://ohdsi.org) community. This role includes extensive online communication, frequent documentation authoring and editing, diagramming critical dataflows, understanding of relevant health technologies, and learning the nuances of oncology research.
The Observational Health Data Sciences and Informatics (or OHDSI, pronounced "Odyssey") program is a multi-stakeholder, interdisciplinary collaborative to bring out the value of health data through large-scale analytics. All our solutions are open-source.
I cannot provide any pay details, but you're welcome to email me.
What's fun about the Coatlicue statute, currently located in the National Museum of Anthropology in Mexico City, is that the earth deity is on the bottom. This statue is so large that one wouldn't be able to "tip" it over to look. Yet, there it is... a carving on the underside where no one can see it. Of course, the museum has a cast of the image adjacent where modern viewers can look at it. More about this kind of fun stuff is in Claudia Brittenham's book, Unseen Art: Making, Vision, and Power in Ancient Mesoamerica (disclaimer: she's my lovey wife).
I like split socks where the toe is separate. They help prevent the sock from shifting on you. These are especially lovely for use with sandals.
Since I have neuropathy, I especially like the ones with tread on the bottom, but that makes them chiral... and it always seems like my drawer has 3 left socks. Expensive ones with treads are sold by "V-Toe Socks, Inc".
[1] https://press.stripe.com/working-in-public [2] https://opencollective.com/become-a-host