I am dubious. Mostly, because preserving and enriching a despot means catering to their whims.
A despot's pet nuclear project is likely to have an authentic red button (provided in any variety of interfaces, telephone, mechanical lock and key, fingerprint authenticated, whatever). If one imagines themselves as a despot, the ego almost demands it.
Between the despot, The Button, and the operational weapons, there are many layers of human factors. Maybe the red button is a placebo, and the underlings, being less suicidal than their singular leader, would never permit the button to perform its dreaded task, but is that assured?
Dude, human factors like personality and mood quickly render safeguards moot, within the atmosphere of a despotic dictatorship.
Open source any amount of safety protocals, and pray that they get used, and you'll acquaint yourself with disappointment.
People who concoct nuclear programs are toying with suicide, and their level of interest in safety can be understood by their decision to weaponize such a thing to begin with.
Meanwhile, cap such a program with a lone psychotic emperor, prone to fits of cruel and unusual punishment, and see what he does on a bad day, as his body ages, and he grows crankier with every waking morning. Now surround him with an echo-chamber of eager-to-please, hawkish, testosterone-fueled military upstarts.