I'm sure that whoever is making this drug is already 10 times ahead of any of us in monetizing this for commercial hair loss applications.
I'll give it my best shot. The reason steroidal creams work is because the steroids are lipid soluble and their mechanism of action involves penetrating cell membranes and bindings to transcription factors in the cytoplasm/nucleus.
A tyrosine kinase inhibitor wouldn't be lipid soluble and therefore wouldn't be able to diffuse across the skin or into the capillaries feeding the hair follicles which is where I'm assuming the positive effect is coming from. (Turning off White Blood Cells).
I'll give it my best shot. The reason steroidal creams work is because the steroids are lipid soluble and their mechanism of action involves penetrating cell membranes and bindings to transcription factors in the cytoplasm/nucleus.
A tyrosine kinase inhibitor wouldn't be lipid soluble and therefore wouldn't be able to diffuse across the skin or into the capillaries feeding the hair follicles which is where I'm assuming the positive effect is coming from. (Turning off White Blood Cells).