It would be good to compare Falcon with Numba: "Numba’s job is to make Python + NumPy code as fast as its C and Fortran equivalents without sacrificing any of the power and flexibility of Python." Like Falcon, Numba is compatible with CPython and whatever extensions you want to use with CPython.
https://github.com/numba/numba
Intro to Numba, parts 1 and 2:
http://continuum.io/blog/numba_growcut
http://continuum.io/blog/numba_performance