I like Macports a lot more. I've never had an issue with any of the packages really besides a few esoteric ones that failed to build or hadn't been updated in a while (and they are usually easy to by updating the portfile). I prefer the segregated environment of macports too, you won't overwrite any system stuff. I got the impression that homebrew wasn't a terribly well thought out tool and was a bit lazy. There's a lot of 'github' culture there which I'm wary of (and by github culture I mean half finished stuff and fancy looking projects lacking rigor). Case in point, it annoys me that their slogan is 'the missing package manager for OSX'. Macports had been around long before they were. I only sometimes wish that Macports had better binary package support.