Yes, my idea behind it is generally draw a sprite, copy it into a new frame, move some parts of it, then reconnect and clean up the ugliness that results from an arm being completely disconnected from a shift in the rest of the image.
It really is a labor of love, best advice really is do as little organic / moving items as possible. They can be added later without feeling the need of "Oh my god not another batch!"
That can work (as I'll dot that for frozen aka slow characters or rage aka fast characters) However certain things just can't be replaced, like a big bite out of a plant or a black eye on another character with blood on the corner of their mouth.
It may be true that books are losing popularity due to digital book readers. I'll still be using books however as a screen just can't compare with the feel, smell, and joy of reading an actual book. They might not be that popular, but they will never die.