Because a language being NP-hard implies it is at least as hard as the hardest NP problems. For any language that is NP-hard, if one had a turing machine that decided the language, one could construct a polynomial time transformation of any language in NP to the NP-hard language to decide it using the NP-hard turing machine.
This doesn't track my experience. I have Ewing's Sarcoma, and my first regimen involved 5 agents: Doxorubicin, Vincristine, Cytoxan, Ifofsfomide, and Etoposide. This [1] appears to be the same plan I used. When that failed, I had a second regimen with Vincristine, Irinotecan, and Temozolomide. After that failed, I had Irinotecan and Trabectidin, followed by Doxil, followed by, Cytoxan and Topotecan, followed by high dose Ifofsfomide. So only two of the treatments I received were single agent, but maybe it depends on the cancer.
At the time, there was essentially a 50/50 chance it was a lab leak or from a wet market. The issue with saying it was a lab leak at that time is that you are essentially gambling the US's relationship with China should it come out that it was a from a wet market. Also, a lot of the discussion regarding the lab leak theory early on seemed to me like it wouldn't be sated even if the US presented sufficient evidence that it was from a wet market.
I haven't gone through the whole article, but it seems to be conflating chroma and saturation. If lightness of a color is scaled by a factor c, then chroma needs to be scaled by that same factor, or saturation won't be preserved, and the color will appear more vibrant then it should.
While one commenter had it somewhat right that HDR has to do with how bright/dark an image can be, the main thing HDR images specify is how far ABOVE reference white you can display. With srgb, 100 percent of all channels is 100 percent white (brightness of a perfect lambertian reflector). Rec 2100 together with rec 2408 specify modern hdr encoding, where 203 nits is 100 percebt white, and above that would be anything brighter (light sources, specular reflection, etc). So if a white image encoded in sdr looks dimmer than hdr for non specular detail, that is probably encoding or decoding error.
Cam16 (as opposed to cam16 ucs) is perception based. It calculates chroma, lightness, and hue, and is based on the munsell color system. Hellwig and Fairchild recently simplifed the model mathematically, improving it's chroma accuracy.( http://markfairchild.org/PDFs/PAP45.pdf) Another, simpler, model is CIELAB, which outputs paramters L, a, and b, where L is lightness, hypot(a,b) is chroma, and arctan2(b,a) is the hue.
You shouldn't be using JCh_to_Jab with CAM16. The CAM16-UCS J'a'b' is a very bizarre construct compared to CIELAB, as a' and b', when converted to cartesian, output hue and ln(1 + 0.0228M)/0.0228, where M is colorfulness. It does not output hue and chroma. Likewise, J' is equal to 1.7*J/(1 + 0.007J). Thus it is almost J, but not.
You should probably just convert straight from XYZ to JCh, without using the UCS.
That being said, I actually revise my thesis. Looking back, Lego used to have age ranges listed: https://images.brickset.com/sets/large/7893-1.jpg , however, it appears all sets now just list a single age with a plus sign. Thus it seems Lego has actually shifted more towards the age simply being capability, with the 18+ designation being the outlier.
The biggest gripe I have with Lego's creation of the 18+ tag is that the age suggestion now has more to do with who lego thinks will enjoy a set, rather than who is capable of building the set. Fans know what they can build, so the age suggestion in my mind was for parents who knew what properties their children enjoyed, but didnt know what their kids were capable of building. I still think that is the case for the other age ranges, but for 18+, I guess lego now thinks adults need to be told what is ok for them to buy. This is most apparent with the BTS set (https://www.lego.com/en-us/search?q=Bts), an 18+ set with simple building techniques targeting a brand mostly enjoyed by teenagers. Compare this to the Airbus heli (https://www.lego.com/en-us/product/airbus-h175-rescue-helico...) which is more aptly labelled at 11+ while having twice as many pieces and being a technic build.
I would argue everyone should learn c purely from a linux/free software point of view. So many open source libraries are written in c, and getting as many eyes as possible on that source code would definitely be beneficial.
Like video, webp uses limited ycbcr, as opposed to jpeg which uses full ycbcr. This leads to grayscale jpeg looking perfect on monitors that use full rgb values, as opposed to webp which will have slight banding issues when displaying grayscale content.
