I suspect AI went that way in radiology not because of the chances of False Negatives, but because radiologist are entrenched in the system and will not yield an insanely lucrative stream of revenue.
The trucker's hitch is usefull because you get a mechanical advantage to tension your line.
Typically, I'd do a bowline on one end first, and tension it with a trucker's hitch. If you go with two bowlines, you end up with a floppy line, not great way to tie a load down.
I assume by limit OP means the remote system's bandwidth.
at 4 billion to 1, there's in practice very little difference between CVE-2022-26143 and what you describe. Both will be capped at the same number by the bandwidth available to the offending system.