While there are rare situations where locking differentials are meaningful, having been in many hair raising off-road situations, including a real life or death one, I'd much rather have AWD and clearance, than 4WD and no clearance.
That is to say, I'm not convinced by the article's hypothesis about locking diffs. It's extremely rare to need to deploy those: beached, or slow starts up vertical surfaces like boulders. An AWD vehicle with good tires and good clearance is really quite good. Bonus points if you don't care about wrecking it.
>Intel also expects to benefit from a U.S. Treasury Department Investment Tax Credit (ITC) of up to 25% on more than $100 billion in qualified investments and eligibility for federal loans up to $11 billion.
>Intel’s investments are expected to create more than 10,000 company jobs and nearly 20,000 construction jobs, and to support more than 50,000 indirect jobs with suppliers and supporting industries.
I've recently moved my laptop over to openSUSE MicroOS (specifically Kalpa, the KDE variant). It shares a bit of philosophy with Vanilla OS. However, in many ways it's almost unrecognizable as a Linux/Unix system.
The way it works (in my incomplete understanding) is that the root filesystem (running on Btfrs), specifically /usr and /var, are actually a read-only image. You can write changes to it, but each time you do, you have to rewrite the image. Each time you boot, you boot that immutable image.
This allows for easy automatic updates. And if it fails to boot after an update, it merely rolls back to the previous working image (crowdstrike take note). This seems to work well provided you don't have to modify the image too much. I installed fprintd, kdeconnect, and wine, and it's still doing OK.
The user applications are almost all Flatpaks. This works well most of the time, but not always. I was a heavy flatpak user before, and I will say that a number of Flatpsk bugs I've run into on other systems, I've not had on Kalpa, so perhaps its Flatpak implementation is better. The biggest issues I have are Flatpaks not being able to communicate with each other as easily as native binaries can.
If you don't have a Flatpak, you can always try to run it in DistroBox. This works..... OK....provided it's a userspace app. But if it's a userspace app, why not run the binary directly? Where distrobox really shines is for running .debs or .rpms on a non-native system. But those are gradually going away thanks to Flatpak anyways. Distrobox does have a fake root mode. I consistently run into boubdary issues with it on Kalpa. I was able to run software in distrobox that required root, and it technically ran, but it couldn't use any audio devices.
Overall, I find Kalpa (and MicroOS) very interesting. There are still edge cases where they break, but I was easily able to work around everything.
The article doesn't list much in the way of tech. LLMs, social media, and advertising hegemons leaving Europe is hardly a tech flight. In fact, it sounds like a best case scenario. Someone call me when Zeiss moves out because they can't compete in Europe, and I'll be concerned Europe is actually losing something of value.
We need more local expertise is really the only answer. Any organization that just outsources everything is prone to this. Not that organizations that don't outsource aren't prone to other things, but at least their failures will be asynchronous.
Yeah, it's partly a tradeoff for convenience. The carpet helps capture dust which makes everything more breathable in the lab as well. I'm sure bigger labs have more sophisticated facilities, but he's just one guy in his attic.
Not really, their margins typically wind up comparably with other manufacturing. They just have way way higher costs. Modern drugs are expensive, for a ton of reasons.
Sanders killed anyone. He was involved in a shootout at a gas station, and a gas station employee got shot by his shootout opponent and killed, which effectively won Sanders the turf war.
60% is freaking nothing in protein space. Like, that's not something to brag about. I could go through and hand edit GFP to 60% identity and get basically GFP still functional at the end.
In grad school, I worked on proteins that were 12%-15% sequence identical but had sub 4 Å RMSDs once the structures were solved.
EDIT: Actually, bragging about it could be a nigerian prince thing, where they do it to scare away investors that might actually hold them to some standard.
I'm curious if you've looked into N-Glycolylneuraminic acid and whether that could be the issue? Does chicken cause an issue for you?
I'm sorry to hear about your Lupus diagnosis, and glad it's in remission. My doctor wanted to diagnose me with Lupus due to the facial rash and arthritis/joint pain, but I came back negative in all the bloodwork, which I think means about 98% sure don't have it. I found that I can treat the joint pain effectively with SSRIs (Fluoxetine, 20 mg is enough to wipe it out after a few weeks). My mother has MCAS and my sister and aunt have UC, so I feel like I'm tripping through a minefield trying to navigate whatever autoimmune issue this is....and I have a PhD in biochemistry.
How much of it is trying to maintain a standard of living they've had their whole life in the face of rampant inflation and insane housing costs?