Question: What of the chemical load that a vaccine or schedule of vaccines might carry? What if immune dysregulation has a tipping point? The tipping point could be a variety of things, including a vaccine. A second question: What if we need the full blown disease, along with the fever to properly train our immune systems? Mr. Manoff's article may have been well-written and fascinating and short on citations but it will raise important questions that need to be asked and answered without fear that everybody will skip their vaccines and we will all die of polio. I am certainly NOT directing this last sentence at you Mr. Swift. I am generally noting with a view to the entire discussion above that sometimes the scientific guild, like all of us, has allowed fear of what might happen to shape their answers to important questions.