The answer in humans does not quite match the answer in mice so far. Possible reasons to explain this discrepancy : might be the lack of a large enough group to study, or a local variation in the groups that does not generalize to mice.
Another option is to skip the antibiotic and use a probiotic to nudge your microbiome toward healthier regions. I am aware of two modern probiotics that might help you:
Both of them are designed thinking of ecosystems more than individual strains (repoopulate has 33 strains, equilibrium has 115). Of course, these aren’t an alternative to FMT if you’re treating a disease… but for general health/wellness I think they’re both quite good.
IMHO, that seems like a bad idea. Two thoughts (these are only very overly generalized opinions, biology is a little bit complicated):
1) You might not get them all, and the ones that survive might transfer the traits of antibiotic survival and pathogenic-ability (if present) to the new population.
2) You would need to ensure that your hyper-specific diet contains the right mixture of microbes, say, you would need to avoid irradiated food, and a bunch of other things. "Bad microbes" coming into an empty gut seems to me like a bad thing.
The answer in humans does not quite match the answer in mice so far. Possible reasons to explain this discrepancy : might be the lack of a large enough group to study, or a local variation in the groups that does not generalize to mice.