FDA Approves First Fast-Acting Drug for Clinical Depression, Works in 1 Week(prevention.com)

15 pointsby FeaturelessBugvor 4 Jahren9 comments

FDA Approves First Fast-Acting Drug for Clinical Depression, Works in 1 Week

https://www.prevention.com/health/a40983448/fda-approves-first-fast-acting-oral-drug-for-clinical-depression-auvelity/

4 comments

ncmncmvor 4 Jahren

Bupropion works very fast by itself, where it works at all. Most likely people who benefit from bupropion get no benefit from the DXM, and vice versa.

So maybe this is supposed to be a scattershot to try two things that might work. If it comes back after a week without, it was the BUP that worked, otherwise the DXM.

joshuvor 4 Jahren

The bup has a modifier effect on the dxm. The fact that it is also an antidepressant is not the main driver.

staticautomaticvor 4 Jahren

If it’s just cough suppressant and buspar, I imagine it could be prescribed off-label instead.

MrWifflesvor 4 Jahren

Bupropion is Welbutrin, not buspar. Just to clarify. Buspar is buspirone.

MrWifflesvor 4 Jahren

So it's Wellbutrin and cough syrup, seriously? Could this be as simple as getting a Wellbutrin RX and taking it with cough suppressant? Surely...surely not?

sterlindvor 4 Jahren

yes, theoretically. the wrinkles are: finding a cough syrup that's pure DXM, and if they're doing anything fancy with extended release (I don't think so, but worth checking.)

your best bet is getting a compounding pharmacy to make the tablets for you, if your insurance doesn't cover this and it's too expensive out-of-pocket.

tsolvor 4 Jahren

Basically. At most they'll add a time release mechanism to release them at certain rates. Well if it works, it works

MrWifflesvor 4 Jahren

Wow. And you know they're probably going to charge something like a $1000 bucks a pill for that too ;-)

kirsebaervor 4 Jahren

This is DXM, a dissociative like ketamin, found in cough medications like Robotussin. You can get quite high on it.